Research Roundup

 

The most important preeclampsia research studies, explained for you. A team of diverse researchers scour the peer-reviewed research journals to highlight the most important, cutting edge studies. We try to cover basic, molecular, clinical and population sciences, and a wide range of topics such as new findings in preeclampsia diagnoses, treatment, prevention, long-term effects, risk factors and etiology of preeclampsia.

Does pravastatin during pregnancy have long-term effects on children?
April 26, 2023
Does pravastatin during pregnancy have long-term effects on children?

Based on limited data, pravastatin use during pregnancy does not appear to have any long-term adverse effects on children. his information will be useful for gaining approval for larger studies to see if pravastatin is actually useful in preventing...

Messenger RNA through ionizable lipid nanoparticles to improve placental blood vessel creation
April 26, 2023
Messenger RNA through ionizable lipid nanoparticles to improve placental blood vessel creation

In this paper, researchers describe how they developed an ionized lipid nanoparticle that is taken into mouse placental cells to increase VEGF.

More sleep, veggies, and movement to reduce risk for a hypertensive disorder of pregnancy
April 26, 2023
More sleep, veggies, and movement to reduce risk for a hypertensive disorder of pregnancy

Identifying the healthful behaviors that lower the risk for a hypertensive disorder of pregnancy can help develop recommendations and prevention programs to support lowering pregnant women’s risk for developing a hypertensive disorder of pregnancy.

One-in-a-trillion – understanding single-cell sequencing to understand preeclampsia
April 26, 2023
One-in-a-trillion – understanding single-cell sequencing to understand preeclampsia

Genetic research over the past 10 years has shown a difference in gene expression in single-cells from placentas of pregnancies with preeclampsia compared to normotensive placentas.

Combining lab results and clinical characteristics to predict HELLP syndrome
April 26, 2023
Combining lab results and clinical characteristics to predict HELLP syndrome

Researchers asked if microRNAs that are linked to cardiovascular disease in non-pregnant people could help predict HELLP syndrome.

Do preeclampsia prediction biomarkers vary in patients of different BMIs?
January 27, 2023
Do preeclampsia prediction biomarkers vary in patients of different BMIs?

This study suggests that women of different BMI classes might have distinct risk profiles for preeclampsia.

What medications may some day be used to treat and prevent preeclampsia?
January 27, 2023
What medications may some day be used to treat and prevent preeclampsia?

Research is being done to make a medicine that can cure preeclampsia a reality. In this article, researchers asked: what are the candidate medicines being studied currently to prevent or treatment preeclampsia?

Further research to investigate protein markers SFLT and PlGF for preeclampsia prediction
January 27, 2023
Further research to investigate protein markers SFLT and PlGF for preeclampsia prediction

This is another study on that journey that shows sFlt1 and PlGF are important proteins in pregnant women’s blood that can tell us about preeclampsia risk.

What barriers do women face to implementing a heart-healthy diet?
January 27, 2023
What barriers do women face to implementing a heart-healthy diet?

For this study, researchers asked: what are the barriers to eating a heart healthy diet for women with high blood pressure or a hypertensive disorder of pregnancy?

High blood pressure in pregnancy is on the rise, especially among Millennial and GenZ patients
September 27, 2022
High blood pressure in pregnancy is on the rise, especially among Millennial and GenZ patients

Two articles were published this quarter that both provide updated statistics about trends in preeclampsia and hypertensive disorders of pregnancy in the United States.

Possible link between genetic changes in women of African ancestry and hypertensive disorders of pregnancy
September 27, 2022
Possible link between genetic changes in women of African ancestry and hypertensive disorders of pregnancy

In this study, HMOX1 gene variants were different depending on ancestry, and these genetic changes could be contributing to the racial disparity in hypertensive disorders of pregnancy.

Researchers identify 2 additional early-pregnancy biomarkers in preeclampsia patients
September 27, 2022
Researchers identify 2 additional early-pregnancy biomarkers in preeclampsia patients

These results highlight two new biomarkers with a possibility of being able to predict timing of onset and subtypes of preeclampsia well before preeclampsia is diagnosed.

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