Last Updated on September 05, 2023
We are working to help research move forward to better understand how to diagnose, treat, and eventually prevent the poor outcomes preeclampsia can have on patients and their families. Learn more about the actions we've taken and the results we've discovered.
Recruiting and retaining nulliparous individuals with a family history of hypertensive disorders of pregnancy to participate in scientific research prior to pregnancy: The Sisterhood Study
ViewLast Updated on October 01, 2023
The Sisterhood Study piloted low-touch, remote recruitment strategies that relied on women with a history of preeclampsia to share study information with family and friends. It aimed to enroll 150 women with a FH of HDP and 150 controls.
Care plan for individuals at risk for preeclampsia: shared approach to education, strategies for prevention, surveillance, and follow-up
ViewLast Updated on September 01, 2023
Last Updated on August 11, 2023
Our data revealed massive dysregulation of gene expression in all cell classes that was almost exclusive to early preeclampsia.
Last Updated on December 09, 2022
Preeclampsia: a report and recommendations of the workshop of the Society for Maternal-Fetal Medicine and the Preeclampsia Foundation
DownloadsLast Updated on November 01, 2022
Last Updated on October 09, 2022
Last Updated on August 31, 2022
Patient journey during and after a pre-eclampsia-complicated pregnancy: a cross-sectional patient registry study
ViewLast Updated on March 03, 2022
Last Updated on February 28, 2022
Information needs and experiences from pregnancies complicated by hypertensive disorders: a qualitative analysis of narrative responses
ViewLast Updated on November 02, 2021
Women’s attitudes, beliefs and values about tests, and management for hypertensive disorders of pregnancy
ViewLast Updated on September 30, 2021
Last Updated on October 03, 2020
Ellen W. Seely, MD,1,2 Ann C. Celi, MD, MPH,2,3 Jaimie Chausmer, FNP-C,4 Cornelia Graves, MD,5 Sarah Kilpatrick, MD, PhD,6 Jacinda M. Nicklas, MD, MPH,7 Mary L. Rosser, MD, PhD,8 Kathryn M. Rexrode, MD, MPH,2,9 Jennifer J. Stuart, ScD,2,9,10 Eleni Tsigas, BA,11 Jennifer Voelker, MS,11 Carolyn Zelop, MD,12,13 and Janet W. Rich-Edwards, ScD, MPH2,9,10
Last Updated on April 28, 2020
Mayri Sagady Leslie, Linda Briggs, Maritza Dowling, Jeongyoung Park - Vision Grant 2017
Last Updated on August 20, 2019
Edwards J, Stuart J, Skurnik G, Roche A, Tsigas E, Fitzmaurice G, Wilkins-Hauge L, Levkoff S, Seely E. Journal of Woman's Health. 2019
Preeclampsia and Future Cardiovascular Disease in Women: What do we know and what can we do?
DownloadsLast Updated on June 12, 2019
The Preeclampsia Foundation - Position Paper
Research Recommendations From the National Institutes of Health Workshop on Predicting, Preventing, and Treating Preeclampsia
ViewLast Updated on April 01, 2019
Last Updated on July 09, 2018
Gammill H, Chettier R, Brewer A, Roberts J, Shree R, Tsigas E, & Ward K. Circulation
Last Updated on July 09, 2017
Tsigas, E. Obstetric Medicine.
Preeclampsia and long-term maternal cardiovascular health: Progress through harmonization of research cohorts and biobanks.
DownloadsLast Updated on June 16, 2016
Staff AC, Redman C, Williams D, Leeson P, Moe K, Thilaganathan B, Magnus P, Steegers E, Tsigas E, Ness R, Myatt L, Poston L, Roberts J. Hypertension. 2016.
Improving the postpartum care of women with a recent history of preeclampsia: a focus group study.
DownloadsLast Updated on June 15, 2016
Skurnik G, Roche A, Stuart J, Rich-Edwards J, Tsigas E, Levkoff S, Seely E. Hypertension in Pregnancy. 2016.
Maternal and perinatal health research priorities beyond 2015: an international survey and prioritization exercise.
DownloadsLast Updated on January 14, 2014
Souza, J, Widmer, M, Gulmezoglu, AM, Lawrie, T, Adejuyigbe, EA, Guillermo, C et al. Reproductive Health 2014, 11:61
Last Updated on December 21, 2013
Seely WE, Rich-Edwards J, Lui J, Nicklas MJ, Saxena A, Tsigas E, Levkoff ES. BMC Pregnancy and Childbirth. 2013,13:240
The brain study: Cognition, quality of life and social functioning following preeclampsia; An observational study.
ViewLast Updated on January 16, 2013
Postma IR, Groen H, Easterling TR, Tsigas EZ, Wilson ML, Porcel J, Zeeman GG. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health 3 (2013) 227–234
Hypertensive disorders of pregnancy and risk of screening positive for Posttraumatic Stress Disorder: A cross-sectional study.
ViewLast Updated on January 16, 2013
Porcel J, Feigal C, Poye L, Postma IR, Zeeman GG, Olowoyeye A, Tsigas E, Wilson M. Pregnancy Hypertension: An International Journal of Women’s Cardiovascular Health 3 (2013) 254–260.
PRE-EMPT (PRE-eclampsia-Eclampsia Monitoring, Prevention and Treatment): A low and middle income country initiative to reduce the global burden of maternal, fetal and infant death and disease related to pre-eclampsia.
ViewLast Updated on January 16, 2013
Von Dadelszen P, Sawchuck D, Hofmeyr GJ, Magee, LA, Bracken H, Mathai M, Tsigas EZ, Teela KC, Donnay F, Roberts JM. Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. Volume 3, Issue 4 , Pages 199-202, October 2013.
Prenatal education is an opportunity for improved outcomes in hypertensive disorders of pregnancy: Results from an internet-based survey.
ViewLast Updated on January 16, 2013
Wallis, A; Tsigas, E; Saftlas, A; Sibai, B. J Matern Fetal Neonatal Med. 2013 Nov;26(16):1565-7.
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.
ViewLast Updated on January 16, 2013
Obstet Gynecol. 2013 Nov;122(5):1122-31. doi: 10.1097/01.AOG.0000437382.03963.88.
Last Updated on January 16, 2012
You WB1, Wolf MS, Bailey SC, Grobman WA. Am J Obstet Gynecol. 2012 May;206(5):431.e1-5. doi: 10.1016/j.ajog.2012.03.006. Epub 2012 Mar 13.
Last Updated on January 16, 2011
World Health Organization.
Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model.
ViewLast Updated on January 16, 2011
Von Dadelszen P, Payne B, Li J, Ansermino JM, Broughton Pipkin F, Côté AM, Douglas MJ, Gruslin A, Hutcheon JA, Joseph KS, Kyle PM, Lee T, Loughna P, Menzies JM, Merialdi M, Millman AL, Moore MP, Moutquin JM, Ouellet AB, Smith GN, Walker JJ, Walley KR, Walters BN, Widmer M, Lee SK, Russell JA, Magee LA; PIERS Study Group (Tsigas E, contributor).Lancet. 2011 Jan 15;377(9761):219-27. doi: 10.1016/S0140-6736(10)61351-7. Epub 2010 Dec 23.
Preeclampsia Integrated Estimate of RiSk Study Group. Abnormal liver function tests as predictors of adverse maternal outcomes in women with preeclampsia.
ViewLast Updated on January 16, 2011
Kozic JR, Benton SJ, Hutcheon JA, Payne BA, Magee LA, von Dadelszen P; Mark Ansermino J, Côté AM, Cundiff G, Gruslin A, Hugo D, Joseph KS, Lee SK, Li J, Lott P, Menzies J, Moutquin JM, Ouellet AB, Russell JA, Shaw D, Smith GN, Keith D, Tawagi G, Wagner B, Walters BN, Mahajan S, Noovao A, Kyle PM, Moore MP, Hall D, Wilhelm Steyn D, Biryabarema C, Mirembe F, Nakimuli A, Broughton Pipkin F, Loughna P, Walker JJ, Grobman W, Tsigas E, Merialdi M, Widmer M. J Obstet Gynaecol Can. 2011 Oct;33(10):995-1004.
Advocacy organisations as partners in pre-eclampsia progress: patient involvement improves outcomes.
ViewLast Updated on January 16, 2011
(book chapter) Tsigas E, Magee L. Best Practice & Research Clinical Obstetrics & Gynecology 25 (2011), pp. 523-536 DOI information: 10.1016/j.bpobgyn.2011.03.001
Review Article: Preeclampsia A Pressing Problem: An Executive Summary of a National Institute of Child Health and Human Development Workshop
ViewLast Updated on January 16, 2007
Ilekis JV, Reddy U, Roberts JM and contributors. Reproductive Sciences 2007; 14; 508.
Patient Perspectives on a Pilot Virtual Follow-up Program After Hypertensive Disorders of Pregnancy: A Qualitative Study
ViewLast Updated on March 10, 2023
Hypertensive disorders of pregnancy (HDPs) are a risk factor for future cardiovascular disease; therefore, follow-up and implementation of early interventions is recommended. We performed a qualitative study to assess the feasibility and user response to a mobile-health tool and virtual consultation aimed at educating people with an HDP on future cardiovascular risk, and at better understanding patients’ priorities for postpartum care.
Last Updated on April 01, 2024
In this validation study of U.S. women, the majority accurately self-reported their preeclampsia diagnosis based on medical record review. A higher proportion of self-reports validated by clinician diagnosis than ACOG criteria, suggesting women remember the diagnosis given by their provider and providers may not always follow or document criteria when making a diagnosis.
Last Updated on January 25, 2024
Using a large insurance-based database, we did not observe a decreased risk of preeclampsia associated with HCQ treatment in pregnancy, although we cannot rule out residual and unmeasured confounding and misclassification. Further studies leveraging large population-based data and prospective collection could characterize how HCQ influences preeclampsia risk in pregnant patients with SLE and among persons at greater risk of hypertensive disorders of pregnancy.
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Your story is needed to improve outcomes for moms like you. Add your voice to critical preeclampsia research to ensure that every story is heard.
Frequently asked questions about the Preeclampsia Registry, a patient-driven registry and biobank.
The Preeclampsia Foundation offers research funding, study recruitment, and other patient engagement services to researchers.
We provide research grant funding to advance progress towards detection, prevention, or treatment of preeclampsia, HELLP syndrome, and other hypertensive disorders of pregnancy.
Preeclampsia is a major cause of maternal and fetal morbidity and mortality. Prompt and accurate diagnosis is necessary to prevent adverse outcomes. A study was completed to determine the accura...
Predicting preeclampsia has proven to be a challenge. Researchers have documented many differences in early pregnancy between those who eventually develop preeclampsia and those who do not. These incl...
The U.S. Preventive Services Task Force (USPSTF) and American College of Obstetricians and Gynecologists (ACOG) guidelines changed in 2021 to help prevent preeclampsia. Low-dose aspirin has been shown...
Hypertensive disorders of pregnancy (HDP), including preeclampsia, affect 1 in 6 pregnancies. HDP is a general term for a range of mild to severe outcomes. Until now there has not been a reliabl...
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Although there is no definitive treatment for preeclampsia, early screening and detection can allow patients to ensure proper management throughout the remainder of the pregnancy. Currently, preeclam...