Category: Risk
Lay Summary: One clinical risk factors for developing preeclampsia in pregnancy is having had preeclampsia before- this is called recurrent preeclampsia. Researchers in this study asked what other factors among persons with a history of preeclampsia can also help predict preeclampsia will occur again in a future pregnancy. Data from 1,028 persons in the Preeclampsia Registry with a history of preeclampsia were used to answer this question. Almost 10 years old now, the Preeclampsia Registry was built to create a partnership between preeclampsia survivors and researchers to help our understanding of preeclampsia. In this study, results showed several predictors of recurrent preeclampsia including: history of migraines, high blood pressure outside of pregnancy (called ‘chronic hypertension’), and first-degree relatives with cardiovascular disease or a placenta-related pregnancy complication.
Take home message: a history of migraines, chronic high blood pressure, and a family history of heart disease may increase your risk for developing preeclampsia in more than one pregnancy.
Link: https://pubmed.ncbi.nlm.nih.gov/35183928/
Citation: Bijl RC, Cornette JMJ, Brewer AN, Zwart IF, Franx A, Tsigas EZ, Koster MPH. Patient-reported preconceptional characteristics in the prediction of recurrent preeclampsia. Pregnancy Hypertens. 2022 Feb 10;28:44-50. doi: 10.1016/j.preghy.2022.02.003. Epub ahead of print. PMID: 35183928.
Each quarter, our team of researchers reviews the most current studies related to hypertensive disorders of pregnancy and selects those studies they feel will be of greatest interest to our community to summarize.
Special thanks to our volunteer research team, who under the leadership of Dr. Elizabeth Sutton, make Research Roundup possible: Alisse Hauspurg, MD Felicia LeMoine, MD Jenny Sones, PhD, DVM, and Robin Trupp, PhD, RN.
Long-term neurodevelopmental follow-up of children exposed to pravastatin in utero If given in early pregnancy pravastatin, (a drug used to lower cholesterol) may decrease the risk of developing pree...
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy (a rat model) Currently the only treatment for preeclampsia starts with delivery of the baby and the placenta....
The nuMom2b study – short for “Nulliparous* Pregnancy Outcomes Study: Monitoring Mothers-To-Be” – is a prospective study that enrolled over 10,000 first time pregnant women acr...
Current Status and Prospects of the Single-Cell Sequencing Technologies for Revealing the Pathogenesis of Pregnancy-Associated Disorders The adult human body is made up of about 100 trillion cells. I...
First-Trimester Screening for HELLP Syndrome—Prediction Model Based on MicroRNA Biomarkers and Maternal Clinical Characteristics Hypertensive disorders of pregnancy and cardiovascular disease a...