...These findings identify EG-VEGF as a novel paracrine regulator of trophoblast invasion. We speculate that a failure to correctly down-regulate placental expression of EG-VEGF at the end of the first trimester of pregnancy might lead to PE...
So, in cell cultures, using a particular inhibitor reversed the biochemical changes in the preeclampsia cells... which suggests a possible role for the chemical it's inhibiting in mucking up the implantation of the placenta. Which might lead us in the direction of tests, or therapies, in the long run.
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