Are tests for predicting PE good enough?

The Preeclampsia Foundation does not necessarily endorse any research or news found in this forum, we just want to share what is out there. Please use your own discretion to evaluate any information you find here.
User avatar
Forum Moderator
Posts: 10203
Joined: Fri Jun 25, 2004 06:36 am

Are tests for predicting PE good enough?

Postby caryn » Sun Jun 07, 2009 00:31 am

...No test had a high level of both sensitivity and specificity of greater than 90%. Where multiple studies were available, only BMI > 34, alpha-fetoprotein, fibronectin (cellular and total), and uterine artery Doppler (bilateral notching) measurements reached specificity above 90%. Only Doppler (any/unilateral notching, resistance index, and combinations) measurements were over 60% sensitive. Studies were of variable quality and most tests performed poorly. Further research should focus on tests which offer much higher levels of sensitivity than tests currently available...

So, the tests still suck. They're planning to focus on developing tests that *overselect* women at risk for preeclampsia, even though that means that some of the women who score a positive test won't develop PE, because a pregnancy monitored more closely for PE where it doesn't develop is very likely to have a better outcome than a pregnancy not monitored closely that *does* develop it.

Information provided on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disorder, or prescribing any medication. The Preeclampsia Foundation presents all data as is, without any warranty of any kind, express or implied, and is not liable for its accuracy, for mistakes or omissions of any kind, nor for any loss or damage caused by a user's reliance on information obtained on the site. Professional opinions on this condition vary greatly. The Preeclampsia Foundation endorses no one course of treatment or "cure".

Return to “Announcements and Preeclampsia in the News”

Who is online

Users browsing this forum: No registered users and 2 guests