Serum Amyloid A Protein and C-Reactive Protein

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Serum Amyloid A Protein and C-Reactive Protein

Postby caryn » Tue Apr 28, 2009 02:18 am

...Plasma levels of C-reactive protein and ceruloplasmin were increased in pregnant women with and without preeclampsia compared to non-pregnant women. Plasma levels of serum amyloid A protein and C-reactive protein were not elevated in women with preeclampsia compared to women with normal pregnancy. Conclusion: The description of preeclampsia as a systemic inflammatory state was not reflected in the plasma levels of serum amyloid A protein and C-reactive protein...

So, this is interesting because we know *something* is wrong with the description of PE as an inflammatory state if those levels aren't elevated the way they are in classic inflammation. The thing about PE is that it's clearly a *novel* immune response, incorporating some elements of innate immunity -- inflammation -- some elements of adaptive immunity -- recognition of foreign proteins by monocytes etc. (white blood cells) -- and some forms of immune response that don't really fall into those two categories, even though those are the only two categories of immune response we really understand at all.

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