Leukocyte activation in PE

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Re : Leukocyte activation in PE

Postby goldielockslizzy » Tue Apr 07, 2009 11:07 pm

....I had high monocytes which are a type of leukocyte in my second pregnancy... I had mild PE this time. hmm.......

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Re : Leukocyte activation in PE

Postby karoliina » Tue Apr 07, 2009 08:36 am

So does this mean that the reason my leucocytes have been up in late pregnancy might be "just" because of PE?


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Leukocyte activation in PE

Postby caryn » Mon Apr 06, 2009 01:54 pm

Altered concentrations of sL-selectin and elastase confirmed leukocyte activation in preeclampsia. These leukocytes showed up-regulation of Nuclear Factor of Kappa light chain gene enhancer in B cells inhibitor (NFkappaB-1A) and cyclin-dependent kinase inhibitor (CDKN)-1A compared with normotensive pregnant women. Interleukin-1 Receptor Antagonist (IL-1RA) and tumor necrosis factor (TNF)-R1 were increased compared with those in non-pregnant controls. Monocyte-derived MP were elevated in preeclamptic patients compared with pregnant women. The numbers of cytotoxic T-cell-derived and granulocyte-derived MP were elevated compared with those of non-pregnant women...


So our immune systems are annoyed; measuring markers of immune activity shows elevations in preeclamptics.

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