Compatibility of HLA-Class II Alleles in Patient C

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Compatibility of HLA-Class II Alleles in Patient C

Postby caryn » Sun Jul 06, 2008 05:15 am

...the number of patient couples with five and six-allele mismatches was significantly lower compared with that in control couples. The same result was obtained as regards the mismatched alleles of the HLA-DR, -DQ, and -DP phenotypes. Conclusion These findings suggest that significant compatibility of HLA-class II alleles between spouses is implicated in the genesis of PE (including GH)...

(This goes back to that thing where the placenta is sending instructions that the mother's body quite literally cannot see, because they don't fit into her molecular receptors, so implantation doesn't proceed normally.)

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