Our results showed that no significant differences in polymorphism frequency of the tested genes, enzyme activity levels or 8-isoprostane levels in the placental tissue were detected between the cases and controls. However, maternal plasma 8-isoprostane level was significantly higher in the cases than in the controls (105.8 vs. 27.9pg/ml, p=0.03).
So isoprostane goes up when leptin goes up, and this probably means the placenta's mucking about with the maternal metabolism...
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