New LDA recommendations

[jedbelv]

Thank you for your response! I will bring it up when I see the mfm to see what she says.

[alviarin]

I'm guessing they changed it to 12 weeks since aspirin may raise the risk of miscarriage in early pregnancy for some women. However it may also help us preeclamptics as you pointed out. I was told to stop taking it at 36 weeks in my last pregnancy.

I wish I had a better answer for you, that sounds like a really good question to ask your OB or MFM. Please let us know what you find out.

ETA: I just went back and read the apirin recommendation again, sounds like it was based on available data. In the future they may have more data which might help them fine tune things better one way or the other.

"In 15 trials, use of low-dose aspirin was initiated between 12 and 28 weeks of gestation. None of the trials initiated use of aspirin before 12 weeks. In 8 trials, use of low-dose aspirin was initiated before 16 weeks. Evidence did not demonstrate benefit of starting aspirin earlier (12 to 16 weeks) rather than later (≥16 weeks) in pregnancy."

"Larger studies investigating aspirin use in the first or early second trimester may improve the evidence base on optimal timing of low-dose aspirin as preventive medication. Other areas of research include optimal therapies that individualize the aspirin dosage and timing of administration"

https://www.uspreventiveservicestaskfor ... medication

[jedbelv]

Hi everyone,
I am expecting baby #5 and am in my 11th week. My last pregnancy I took LDA from week 8 or 9 to week 18 with really good outcomes. For the first time since being diagnosed with chronic hypertension at the age of 24 I had perfect blood pressure readings during second and third trimesters without medication, my daughter weighed 8lbs 3oz and was born full term. In my previous pregnancy, my son was born 5lbs 8oz and blood pressure was completely uncontrollable throughout. The only thing I did differently this last pregnancy was take LDA from around week 9 to week 18. That was the recommendation in 2013 since "trophoblastic invasion of the spiral arteries starts at 8 weeks of gestation and is completed at 16–20 weeks of gestation". Now I read that it has changed to taking it from week 12 to week 34. I am confused as to why it would have to be taken beyond 18 -20 weeks? Also, why it is recommended to start at 12 weeks versus earlier. I have searched but cannot find an explanation.
I started taking at 9 weeks this time around like I did last time but am at a loss on when to stop. I feel as if LDA has side effects for me ( ringing of the ears, jitteriness, and heartburn) so I do not want to take it longer than needed.