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 Preeclampsia and low progesterone...
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atvlady
Junior Member

Delissa
US
333 Posts

Posted - 11/03/2009 :  6:57:12 PM  Show Profile  Visit atvlady's Homepage  Send atvlady a Yahoo! Message  Reply with Quote
Is there a link? I was told today that progesterone "keeps you pregnant."

Delissa(36) Hubby(43)
#1 Rissa-Janelle "Darren" King born 6-6-09 10:33 p.m. passed 6-6-09 11:53 p.m. Twenty weeks one day gestational, 192 grams (6.8 ounces), 9 inches long. Severe HELLP, severe Pre-e and severe PIH.
#2 TTC as of October, 24 2009. HELLP, pre-e and all your ugly buddies, STAY AWAY!

Learn from the past, build for the future.

mom29
Senior Member

USA
1189 Posts

Posted - 11/03/2009 :  7:08:33 PM  Show Profile  Reply with Quote
Never heard of it being linked. I know that women whose progesterone levels are too low will miscarry.
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rebecca2
Junior Member

US
104 Posts

Posted - 11/03/2009 :  8:40:01 PM  Show Profile  Reply with Quote
Delissa, progesterone is a very important hormone that supports the pregnancy until the placenta takes over at around 8-10 weeks. As mentioned above, low progesterone might be a sign for miscarriage. However, it is a controversial topic among some OB's as to whether low progesterone is the cause of the miscarriage or the result of an impending miscarriage. Sometimes progesterone is given to women in the 2nd & 3rd trimesters if they suspect PTL or incompetent cervix.

I take progesterone injections during the first several weeks (10+/-) of my pregnancies because I have to do IVF to get pregnant and it is standard protocol for IVF patients. After I lost my daughter I searched everywhere to see if there was a link between progesterone & PE. I didn’t find anything linking the two, but maybe someone else has seen something.

Becky

DD Addison 3/11/09-3/11-09, born 26w5d due to severe PE

Edited by - rebecca2 on 11/03/2009 8:40:38 PM
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missgamecock
Senior Member

kirstensara5
USA
6058 Posts

Posted - 11/04/2009 :  07:39:16 AM  Show Profile  Reply with Quote
I had extremely low progesterone with Cate and absolutely believe that if I had not supplemented, I would have lost her. I also had preterm labor with her that was being stopped with procardia. I saw the links you are talking about when I was pregnant and it is controversial. Something about the placenta not implanting right, leads to the progesterone not producing. Of course pe is a problem with the placenta. Even now that I am NOT pregnant, my ob just put me on a 5 x's a dose of progesterone because my IUD perforated and had to be removed.

Sabrina, mom of Kirsten Scout DOB 3/27/99, 5lbs, 1oz., 36 weeks 0 days, severe PE, & Sara Grace DOB 6/28/05, 6lbs 1oz., Severe PIH, 35 weeks 5 days. #3 Peyton, lost at 13 weeks 3 days on 2/21/08
4th - Lost at 5 weeks 4/30/08.
DD #3, Caitlyn Elyse (Catie), a Rainbow Baby, DOB 1/16/09, 5lbs 7 ozs, 36 weeks, Diagnosed w/ chronic HTN, RT Uterine Artery Notching, and mild PE.
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jend01
Junior Member

jend01
US
138 Posts

Posted - 11/04/2009 :  11:02:05 AM  Show Profile  Click to see jend01's MSN Messenger address  Reply with Quote
I had very low progesterone with my first pregnancy, started taking supplements, but they weren't soon enough so I miscarried early in the first trimester. With Eian, my doctor didn't hesitate at all to put me on supplements. Actually when I called for the appointment she called them in for me before even checking my levels. If I have anymore pregnancies I'm sure they will be treated the same way.

-Jennifer
Mom to Eian Marshall born 07/08/08 36+ weeks due to borderline PE symptoms. (healthy baby 6lbs 1oz, no NICU) :)
led to eclamptic seizures and cardiac arrest 4 days PP and 6 days in ICU to stabalize. Chronic hypertensive and PTSD today, but getting better on the meds.
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Caryn
Ask the Experienced Moderator

CarynFamily
USA
7655 Posts

Posted - 11/04/2009 :  11:24:45 AM  Show Profile  Reply with Quote
The only post I can find in the Experts forum on the topic of progesterone is here, and is mostly about how women with chronic hypertension will see their pressures rise if they're supplemented with progesterone. (This is why I'm not a candidate for hormonal birth control.)

IIRC progesterone competes with aldosterone for a receptor that's involved in maternal volume expansion. Insofar as there's any link with PE, that might be it. But there's no data suggesting a benefit from supplemental progesterone in PE prevention.

Science is getting us closer to finding a cause, and even a cure. The articles you don't want to miss:
The Preeclampsia Puzzle (New Yorker) and Silent Struggle: A New Theory of Pregnancy (New York Times)
Looking for recent articles and studies?
Caryn, who is not a doctor and who talks about science stuff *way* too much
DS Oscar born by emergent C-section at 34 weeks for fetal indicators, due to severe PE
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atvlady
Junior Member

Delissa
US
333 Posts

Posted - 11/04/2009 :  1:05:19 PM  Show Profile  Visit atvlady's Homepage  Send atvlady a Yahoo! Message  Reply with Quote
Thanks all of you.
Caryn I TOTALY agree on the hormonal BC. I will NEVER take that again, now that I know the dangers of it!
Just to run this by everyone, I saw my OB this morning. She says progesterone does *not* have anything to do with pre-e. It could help keep you pregnant though.
FFT

Delissa(36) Hubby(43)
#1 Rissa-Janelle "Darren" King born 6-6-09 10:33 p.m. passed 6-6-09 11:53 p.m. Twenty weeks one day gestational, 192 grams (6.8 ounces), 9 inches long. Severe HELLP, severe Pre-e and severe PIH.
#2 TTC as of October, 24 2009. HELLP, pre-e and all your ugly buddies, STAY AWAY!

Learn from the past, build for the future.
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