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Caryn
Ask the Experienced Moderator
USA
7655 Posts |
 Posted - 10/26/2009 : 7:34:35 PM
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Of 35 women, 17 were allocated to sildenafil and 18 to placebo. There was no difference in time from randomisation to delivery in the two treatment groups, with a median time of 4 days (range 1-15) in the sildenafil group and 4.5 days (range 1-30) in the placebo group. Sildenafil achieved maximum drug concentrations of 48 ng/ml, 88 ng/ml, and 271 ng/ml after 3 days of 20 mg, 40 mg and 80 mg tid, respectively.
http://www.ncbi.nlm.nih.gov/pubmed/19843000
Darn it, Viagra doesn't seem to be working for us. The idea was that it was a vasodilator, and might buy enough time for steroids, but it didn't delay delivery in this (very small) study.
Information provided on this site is provided for informational purposes only and is not meant to substitute for the advice provided by your own physician or other medical professional. You should not use the information contained herein for diagnosing or treating a health problem or disorder, or prescribing any medication. The Preeclampsia Foundation presents all data as is, without any warranty of any kind, express or implied, and is not liable for its accuracy, for mistakes or omissions of any kind, nor for any loss or damage caused by a user's reliance on information obtained on the site. Professional opinions on this condition vary greatly. The Preeclampsia Foundation endorses no one course of treatment or "cure". |
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Blythe
Ask the Experienced Moderator
USA
2081 Posts |
Posted - 10/26/2009 : 8:42:24 PM
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| Darn it, that did sound hopeful when I heard about it before. |
Heather - mom to
DS #1 - 7/18/03, 37 weeks - Mild PE, 5lbs, 8oz, 4 days in NICU
DS #2 - 8/11/06, 36 1/2 weeks, 6lbs, 14oz!!! Induced for diagnostic BP. No NICU!
DD #3 - 9/10/09, high bp at 33 1/2 weeks, induced at 37 weeks, 5 pounds, 12 ounces - healthy girl!
"Thank God for the internet - otherwise my children would be raised in a med school library" |
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sildenafil for the treatment of preeclampsia.
